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Year : 2019  |  Volume : 13  |  Issue : 3  |  Page : 106-109

Two nights in one day: A case report of paraganglioma in sickle cell disease and a review of the literature

1 Department of Surgery, University of Benin Teaching Hospital, Benin City, Edo State, Nigeria
2 Department of Pathology, University of Benin Teaching Hospital, Benin City, Edo State, Nigeria
3 Department of Pathology, National Hospital, Abuja, Nigeria

Correspondence Address:
Clement Odigie Osime
Department of Surgery, University of Benin Teaching Hospital, PMB 1111, Ugbowo, Benin City, Edo State
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/phmj.phmj_12_19

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Background: Sickle cell disease (SCD) is a chronic lifelong disease seen typically in Sub-Saharan Africans, the Mediterranean region and parts of Asia. The condition may be associated with other clinical entities. Aim of Presentation: We present a case of malignant variant of paraganglioma in a 34-year-old SCD patient to highlight the fact that some very rare clinical entities may be found in this category of patients. Case Report: Miss B.O. was a 34-year-old SCD patient who presented with features of an intra-abdominal mass. Incisional biopsy done from a mass arising from the left adrenal gland confirmed a malignant variant of paraganglioma. Post-exploratory laparotomy, the patient's clinical state deteriorated and she died 25 days after surgery. Conclusion: Malignant variant of a paraganglioma, a very rare clinical condition, may be found in SCD patients.

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